抗MMP14抗体(anti- MMP14 antibody)

　　名称：抗MMP14抗体(anti- MMP14 antibody)

　　货号：FNab05236

　　适应种属：人源，小鼠，大鼠

　　规格：100ug(微克)

　　状态：液体

　　纯化方法：免疫亲和纯化

　　纯度：经sds-page分析,纯度大于95%

　　宿主：兔

　　亚型：igg

　　存储：用添加了0.02%叠氮化钠和50%甘油的pbs溶解,ph值7.3,可在-20℃下保存12个月（避免反复冻融）

　　免疫原：matrix metallopeptidase 14 (membrane-inserted)

　　免疫原别称：MMP-14

　　分子量：65 kDa

　　验证应用：ELISA, WB, IHC

　　建议稀释比例：WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

　　克隆性：多克隆

　　uniprot id：P50281

　　背景介绍：Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion。

　　图像：

　　Immunohistochemistry of paraffin-embedded human liver cancer using FNab05236 (MMP14 Antibody) at dilution of 1:100。

　　mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05236 (MMP14 antibody) at dilution of 1:1000。