抗VEGFR2抗体(anti- VEGFR2 antibody)

　　名称：抗VEGFR2抗体(anti- VEGFR2 antibody)

　　货号：FNab09795

　　适应种属：人源，小鼠，大鼠

　　规格：100ug(微克)

　　状态：液体

　　纯化方法：免疫亲和纯化

　　纯度：经sds-page分析,纯度大于95%

　　宿主：兔

　　亚型：igg

　　存储：用添加了0.02%叠氮化钠和50%甘油的pbs溶解,ph值7.3,可在-20℃下保存12个月（避免反复冻融）

　　免疫原：Vascular endothelial growth factor receptor 2

　　免疫原别称：CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2

　　分子量：200 kDa

　　验证应用：ELISA, IHC, WB, FC

　　建议稀释比例：WB: 1:500-1:1000; IHC: 1:50-1:500

　　克隆性：多克隆

　　uniprot id：P35968

　　背景介绍：KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas。

　　图像：

　　Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab09795 (VEGFR2 antibody) at dilution of 1:200。

　　human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09795 (VEGFR2 Antibody) at dilution of 1:600。