抗USP1抗体(anti-USP1 antibody)

　　名称：抗USP1抗体(anti-USP1 antibody)

　　货号：FNab09302

　　适应种属：人源，小鼠，大鼠

　　规格：100ug(微克)

　　状态：液体

　　纯化方法：免疫亲和纯化

　　纯度：经sds-page分析，纯度大于95%

　　宿主：兔

　　亚型：igg

　　存储：用添加了0.02%叠氮化钠和50%甘油的pbs溶解，ph值7.3，可在-20℃下保存12个月（避免反复冻融）

　　免疫原：ubiquitin specific peptidase 1

　　免疫原别称：Deubiquitinating enzyme 1, hUBP, ubiquitin specific peptidase 1, Ubiquitin thiolesterase 1, UBP, USP1

　　分子量：100 kDa

　　验证应用：ELISA, WB, IHC, IP

　　建议稀释比例：WB: 1:200-1:2000; IHC: 1:20-1:200；IP: 1:200-1:1000

　　克隆性：多克隆

　　uniprot id：O94782

　　背景介绍：Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335) . Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995) . Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029)。

　　Immunohistochemistry of paraffin-embedded human cervical cancer using FNab09302 (USP1 antibody) at dilution of 1:100。

　　IP Result of anti-USP1 (IP:FNab09302, 3ug; Detection:FNab09302 1:300) with HEK-293 cells lysate 3200ug。

　　HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09302 (USP1 antibody) at dilution of 1:300。