抗NEDD4L抗体(anti- NEDD4L antibody)

　　名称：抗nedd4l抗体(anti- nedd4l antibody)

　　货号：fnab05646

　　适应种属：人源，大鼠，小鼠

　　规格：100ug(微克)

　　状态：液体

　　纯化方法：免疫亲和纯化

　　纯度：经sds-page分析,纯度大于95%

　　宿主：兔

　　亚型：igg

　　存储：用添加了0.02%叠氮化钠和50%甘油的pbs溶解,ph值7.3,可在-20℃下保存12个月（避免反复冻融）

　　免疫原：neural precursor cell expressed, developmentally down-regulated 4-like

　　免疫原别称：kiaa0439, nedl3

　　分子量：113 kda

　　验证应用：elisa, wb, ihc, if

　　建议稀释比例：wb: 1:500 - 1:2000; ihc: 1:50 - 1:200; if: 1:50 - 1:200

　　克隆性：多克隆

　　uniprot id：q96pu5

　　背景介绍：this gene encodes a member of the nedd4 family of hect domain e3 ubiquitin ligases. hect domain e3 ubiquitin ligases transfer ubiquitin from e2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. the encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, enac. single nucleotide polymorphisms in this gene may be associated with essential hypertension. alternatively spliced tran variants encoding multiple isoforms have been observed for this gene。

　　图像：

　　immunohistochemistry of paraffin-embedded human prostate using fnab05646(nedd4l antibody) at dilution of 1:200。

　　k-562 cells were subjected to sds page followed by western blot with fnab05646(nedd4l antibody) at dilution of 1:1000。