抗Transferrin抗体(anti-Transferrin antibody)

　　名称：抗Transferrin抗体(anti-Transferrin antibody)

　　货号：FNab08929

　　适应种属：人源，大鼠，小鼠

　　规格：100ug(微克)

　　状态：液体

　　纯化方法：免疫亲和纯化

　　纯度：经sds-page分析，纯度大于95%

　　宿主：兔

　　亚型：igg

　　存储：用添加了0.02%叠氮化钠和50%甘油的pbs溶解，ph值7.3，可在-20℃下保存12个月（避免反复冻融）

　　免疫原：transferrin

　　免疫原别称：Beta 1 metal binding globulin, DKFZp781D0156, PRO1557, PRO2086, Serotransferrin, Siderophilin, TF, Transferrin

　　分子量：77 kDa

　　验证应用：ELISA, WB, IHC, IF

　　建议稀释比例：WB: 1:200-1:1000; IHC: 1:20-1:200

　　克隆性：多克隆

　　uniprot id：P02787

　　背景介绍：Serotransferrin (TF) is a 77 kDa secreted protein which is also named as transferrin, siderophilin, beta-1 metal-binding globulin and belongs to a family of homologous iron-binding glycoproteins that encompasses lactoferrin (found both intracellular and in secretions, including milk) , melanotrasferrin (present on melanoma cells) and ovotransferrin (present in egg white) . TF is a multi-function protein with a primary role in transporting iron in a safe, redox-inactive state from absorption to utilization or storage sites around the body. The association of Tf with the immune system derives from its ability to restrict serum free-iron levels, creating low-iron environments where the infection capacity of pathogenic microorganisms is limited. TF is expressed predominantly in the liver and secreted in plasma, but lower amounts can be synthesized in other tissues such as the brain and the testis。

　　Immunohistochemistry of paraffin-embedded human hepatocirrhosis using FNab08929 (TF antibody) at dilution of 1:50。

　　mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab08929 (TF antibody) at dilution of 1:400。