Anti-Rem2 antibody LM851014R

Anti-Rem2 antibody

产品描述

　　REM2 (RAS (RAD and GEM)-like GTP binding 2) is a 340 amino acid cell membrane protein that functions as a GTPase and belongs to the RGK family as well as the small GTPase superfamily. A suppressor of the p53 pathway, REM2 also mediates the fibroblastic growth factor 2 (FGF-2) signaling pathway and is involved in maintaining the proliferation of human embryonic stem cells. Expressed in kidney and brain, REM2 is encoded by a gene that maps to human chromosome 14q11.2. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

　　产品名称Anti-Rem2 antibody

　　分子量37 kDa

　　种属反应性Human

　　验证应用IHC-P,FC

　　抗ti类型兔多抗

　　免疫原Recombinant protein

　　偶联Non-conjugated

性能

　　形态Liquid

　　浓度1 mg/mL.

　　存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

　　存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

　　亚型IgG

　　纯化方式Peptide affinity purified.

　　亚细胞定位Cell membrane.

　　数据链接Q8IYK8

　　其它名称

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　　etID309896.20 antibody

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应用

　　ICC: 1:50-1:200

　　IHC-P: 1:50-1:200

　　FC: 1:50-1:100

　　WB: 1:500

本产品只适用于科研，不能用于临床诊断。严禁用于临床医疗及其他非科研用途！