Anti-BAI1 antibody LM80093R

anti-bai1 antibody

产品描述

　　angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. angiogenesis has been shown to be essential for growth and metastasis of solid tumors. in order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. bai1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. there are two other brain-specific angiogenesis inhibitor genes, designated bai2 and bai3 which along with bai1 have similar tissue specificities and structures, however only bai1 is tranionally regulated by p53. bai1 is postulated to be a member of the secretin receptor family,

　　产品名称anti-bai1 antibody

　　分子量130-170 kda

　　种属反应性human, rat, mouse

　　验证应用wb, ihc-p

　　抗ti类型兔多抗

　　免疫原synthetic peptide of bai1

　　偶联non-conjugated

性能

　　形态liquid

　　浓度1 mg/ml.

　　存放说明store at +4℃ after thawing. aliquot store at -20℃ or -80℃. avoid repeated freeze / thaw cycles.

　　存储缓冲液liquid in pbs containing 50% glycerol, 0.5% bsa and 0.02% sodium azide.

　　亚型igg

　　纯化方式immunogen affinity purified.

　　数据链接swissprot: o14514 human

　　其它名称

　　brain-specific angiogenesis inhibitor 1 antibody;

应用

　　wb: 1:500-1:2000

　　ihc-p: 1:100-1:300

本产品只适用于科研，不能用于临床诊断。严禁用于临床医疗及其他非科研用途！