Anti-NLRP3 antibody LM870672R

Anti-NLRP3 antibody

产品描述

　　Cryopyrin interacts selectively with apoptosis associated specklike protein containing a CARD domain (ASC). This complex may function as an upstream activator of NFkB signaling and caspase-1 activation. The complex also inhibits TNFa induced activation and nuclear translocation of RelA/NFkB p65. Mutations in Cryopyrin and Pyrin proteins are responsible for several autoinflammatory disorders in humans, including familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and chronic infantile neurologic cutaneous and articular syndrome (CINCA).

　　产品名称Anti-NLRP3 antibody

　　分子量85 kDa

　　种属反应性Human,Mouse

　　验证应用WB,ICC,IHC-P,FC

　　抗ti类型兔多抗

　　免疫原Peptide.

　　偶联Non-conjugated

性能

　　形态Liquid

　　浓度1 mg/mL.

　　存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

　　存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

　　亚型IgG

　　纯化方式Peptide affinity purified.

　　亚细胞定位Nucleus. Cytoplasm. Secreted.

　　数据链接Q96P20 Human

　　Q8R4B8 Mouse

　　其它名称

　　AGTAVPRL antibody

　　AII/AVP antibody

　　Angiotensin/vasopressin receptor AII/AVP like antibody

　　more

应用

　　WB: 1:500-1:2,000

　　ICC: 1:500-1:2,000

　　IHC-P: 1:50-1:200

　　FC: 1:50-1:100

本产品只适用于科研，不能用于临床诊断。严禁用于临床医疗及其他非科研用途！