Anti-Bcl x antibody LM8009R

　　Anti-Bcl-x antibody

　　产品描述

　　Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis (1). Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2 (2). It has been found that heterodimerization with Bax does not seem to be required for anti-apoptotic activity (3). Since Bcl-xL can form an ion channel in synthetic lipid membranes, there is a strong possibility that this property plays a role in heterodimerization-independent cell survival (4). The Bcl-X(S) isoform promotes apoptosis.

　　产品名称Anti-Bcl-x antibody

　　分子量26 (Bcl-xL) / 19 (Bcl-xS)

　　种属反应性Human,Mouse,Rat

　　验证应用WB,ICC,IHC-P,FC,IP

　　抗ti类型兔多抗

　　免疫原peptide

　　偶联Non-conjugated

　　性能

　　形态Liquid

　　浓度1 mg/mL.

　　存放说明Store at -20 ℃. Stable for 12 months from date of receipt

　　存储缓冲液1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

　　亚型IgG

　　纯化方式Protein A affinity purified.

　　亚细胞定位Cytoplasm, Nucleus membrane, Cytoplasmic vesicle Mitochondrion matrix, Mitochondrion outer/ inner membrane

　　数据链接Q07817

　　其它名称

　　more

　　Apoptosis regulator Bcl X antibody

　　Bcl 2 like 1 antibody

　　Bcl 2 like 1 protein antibody

　　应用

　　WB: 1:500-1,000

　　ICC: 1:100

　　IHC-P: 1:50-100

　　IP: 1:10

　　FC: 1:50

　　Fig1: Western blot analysis of K562 cell lysate using anti-Bcl-x.

　　Fig2: Immunohistochemical analysis of human paraffin-embedded prostate carcinoma tissue using anti-Bcl-x.

　　本产品只适用于科研，不能用于临床诊断。严禁用于临床医疗及其他非科研用途！