Anti-ROBO1 antibody LM8706-24R

Anti-ROBO1 antibody

产品描述

　　Specific cells in the midline separate the left and right halves of the central nervous system and play many roles in guiding the growth cone behavior. In vertebrate spinal cord, insect abdominal nerves and nematodes, midline cells produce induced cues, such as nectins and slits, respectively, as attractants and repellents. respectively. These cells can serve as gatekeepers to prevent axons from passing through the midline and to guide the growth cone in response to the switching of lead cues beyond the crossing. One such gatherer, Robo, is an axon guidance receptor that defines a new subfamily of proteins from fruit flies to mammalian conserved Ig superfamily proteins. Robo acts as a receptor for the repellent Slit and functions in a cell-autonomous manner Non-intersecting axons express high levels of Robo and cross axons to express low levels of Robo and then reach midline and high levels of crossover. Robo1 and Robo2 are two human homologs of Drosophila megalopolis. Robo1 is also homologous to the C. elegans gene sax3, while Robo2 is homologous to zebrafish genes.

　　产品名称Anti-ROBO1 antibody

　　分子量180 kDa

　　种属反应性Human,Mouse

　　验证应用ICC,IHC-P

　　抗ti类型兔多抗

　　免疫原Peptide

　　偶联Non-conjugated

性能

　　形态Liquid

　　浓度1 mg/mL.

　　存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

　　存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

　　亚型IgG

　　纯化方式Peptide affinity purified.

　　亚细胞定位Membrane.

　　数据链接Q9Y6N7 Human

　　O89026 Mouse

　　其它名称

　　Deleted in U twenty twenty antibody

　　DUTT 1 antibody

　　DUTT1 antibody

　　more

应用

　　ICC: 1:100-1:500

　　IHC-P: 1:50-1:200

本产品只适用于科研，不能用于临床诊断。严禁用于临床医疗及其他非科研用途！