Anti-PD-L2 antibody LM85751R

Anti-PD-L2 antibody

产品描述

　　Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. induction:Up-regulated by IFNG stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4. Belongs to the immunoglobulin superfamily. BTN/MOG family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. subunit:Interacts with PDCD1. tissue specificity:Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.

　　产品名称Anti-PD-L2 antibody

　　分子量30 kDa

　　种属反应性Human

　　验证应用WB, IHC-P

　　抗ti类型兔多抗

　　免疫原Synthetic peptide from human protein at AA range: 31-80

　　偶联Non-conjugated

性能

　　形态Liquid

　　浓度1 mg/mL.

　　存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

　　存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

　　亚型IgG

　　纯化方式Immunogen affinity purified.

　　数据链接SwissProt: Q9BQ51 Human

　　其它名称

　　Programmed cell death 1 ligand 2 (PD-1 ligand 2) (PD-L2) (PDCD1 ligand 2) (Programmed death ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD antigen CD273) antibody;

应用

　　WB: 1:500-1:2000

　　IHC-P: 1:50-200

本产品只适用于科研，不能用于临床诊断。严禁用于临床医疗及其他非科研用途！